(Phys.org) —In a comprehensive study, scientists at the Friedrich Miescher Institute for Biomedical Research identified the molecular logic underlying the retention of histones and their marks during the development of the sperm. These findings set the stage to address a fundamental question in epigenetics: whether and how chromatin marks in sperm are passed on to the next generation and contribute the epigenetic inheritance of traits shaped by experience or the environment. Their results were recently published online in Nature Structural & Molecular Biology.
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