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Team finds how a key enzyme of the spliceosome exerts its controlling function

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To sustain life, processes in biological cells have to be strictly controlled both in time and in space. Research workers at the Max Planck Institute for Biophysical Chemistry in Göttingen and Freie Universität Berlin have elucidated a previously unknown mechanism that regulates one of the essential processes accompanying gene expression in higher organisms. In humans, errors in this control mechanism can lead to blindness. This discovery was published in the renowned scientific journal Science.

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